Men and women estrogen regulate various body systems

While both men and women produce estrogen to regulate various body systems, women experience a profound decrease in estrogen production later in life.
The sudden decrease triggers a host of physiological changes that are collectively referred to as menopause.
What organ is responsible for this loss of estrogen in women? What effects does this have on the body. One effect has to do with bone regulation and
women can experience osteoporosis. What can be done to minimize the impacts of a sudden reduction in estrogen? What dangers does this therapy involve?
Grading Rubric:
4 points – Identified organ involved and described physiological changes
3 points – Identified therapy used to combat effects of menopause
3 points – Discussed the dangers of possible therapies